Spreading Plague
Enchantment
Whenever a creature enters, destroy all other creatures that share a color with it. They can't be regenerated.
- CMC
- 5
- Mana cost
- Color identity
- B
- Rarity
- rare
- Set
- Invasion
- Price
- $12.18
- EDHREC rank
- #14872
Spreading Plague turns every creature that enters the battlefield into a board wipe for its own color — opponents can't rebuild through it without changing colors entirely. Pair it with Painter's Servant naming a single color and nothing survives the turn it drops.
Format Analysis
Where it lives, where it can’t
| Format | Verdict |
|---|---|
| commander | legal |
| legacy | legal |
| modern | not legal |
| pioneer | not legal |
| standard | not legal |
| vintage | legal |
| pauper | not legal |
| oathbreaker | legal |
Spreading Plague is a Commander card through and through — the enchantment's slow, cumulative pressure is exactly what a 100-card singleton game rewards, and multiplayer boards full of same-colored creatures make each trigger matter more. In Legacy and Vintage, it's legal but irrelevant: five mana for a conditional continuous effect doesn't survive contact with Force of Will, and faster threats close games before Spreading Plague stabilizes anything. Oathbreaker is the one other format worth mentioning, where the lower starting life total and tighter card pool mean the board-control angle can actually close a game.
Key Combos
Combo lines featuring this card



Spreading PlaguePainter's ServantEldrazi Monument
Destroy all creatures opponents control whenever a creature enters the battlefield; Lock
View on Commander Spellbook ↗


Spreading PlagueDarkest HourEldrazi Monument
Destroy all creatures opponents control whenever a creature enters the battlefield; Lock
View on Commander Spellbook ↗


Spreading PlaguePainter's ServantAvacyn, Angel of Hope
Destroy all creatures opponents control whenever a creature enters the battlefield; Lock
View on Commander Spellbook ↗


Spreading PlagueDarkest HourAvacyn, Angel of Hope
Destroy all creatures opponents control whenever a creature enters the battlefield; Lock
View on Commander Spellbook ↗Budget Alternatives
Cheaper options that do most of the same work
Spreading Plague's continuous color-based destruction is genuinely unusual — nothing else does exactly that for less. Engineered Plague and Meathooks Massacre both punish creature-heavy boards at lower price points, but they're one-shot or type-based rather than color-based, so they won't replicate the combo ceiling Spreading Plague has with Painter's Servant.
Price Context
Current price
$12.18 mid tier
At $12.18, Spreading Plague sits in mid-tier territory — expensive enough to feel like a real purchase, cheap enough that a single combo inclusion justifies it. It's a Reserved List card, so the supply ceiling is fixed and the price reflects genuine scarcity rather than just demand.
Explore
Sources
Updated . Data from Scryfall, EDHREC, and Commander Spellbook.