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Skithiryx, the Blight Dragon

Legendary Creature — Phyrexian Dragon Skeleton

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

CMC
5
Mana cost
{3}{B}{B}
Color identity
B
Rarity
mythic
Set
Marvel Universe
Price
$11.47
EDHREC rank
#2659
Buy on TCGplayer
Skithiryx, the Blight Dragon card art
Skithiryx, the Blight Dragon threatens a ten-poison kill out of nowhere — five points of infect with haste and built-in regeneration is a clock that closes games the turn it lands. The cost is a five-mana mono-black identity that locks you out of support tools available to infect shells like Ixhel, Scion of Atraxa, but in Scion of the Ur-Dragon decks and anywhere black has room for a one-shot threat, it earns its slot.

Best Commanders

Commanders with the highest synergy

01
Ixhel, Scion of Atraxa

Ixhel, Scion of Atraxa

45.4% of decks · synergy 0.43

Ixhel, Scion of Atraxa appears in 45% of Ixhel decks because the two cards are building toward the same kill condition — Ixhel poisons opponents through combat and its triggered ability, and Skithiryx, the Blight Dragon closes out anyone already at five-plus poison counters in a single hasted swing.

02
Sivitri, Dragon Master

Sivitri, Dragon Master

37.6% of decks · synergy 0.37

Sivitri, Dragon Master tutors directly for dragons, and Skithiryx, the Blight Dragon is one of the most lethal hits — Sivitri, Dragon Master builds a board of dragons with specific roles, and Skithiryx fills the finisher slot, threatening poison kills that invalidate life-gain-heavy defensive strategies.

03
Vishgraz, the Doomhive

Vishgraz, the Doomhive

29.8% of decks · synergy 0.28

Vishgraz, the Doomhive produces a board of poison-counter-dealing tokens that soften opponents, and Skithiryx, the Blight Dragon converts that setup into a sudden lethal swing — together they represent both the incremental and the explosive infect win condition in the same list.

04
Mimeoplasm, Revered One

Mimeoplasm, Revered One

25.9% of decks · synergy 0.25

Mimeoplasm, Revered One can clone Skithiryx, the Blight Dragon directly, inheriting infect, haste, and regeneration while potentially entering with +1/+1 counters that push it past the ten-power threshold for a one-hit poison kill.

05
The Mimeoplasm

The Mimeoplasm

23.1% of decks · synergy 0.22

The Mimeoplasm is the older version of the same play pattern — exile Skithiryx, the Blight Dragon from a graveyard as the +1/+1 counter source, stack it on a large creature, and enter the battlefield with infect and a power count that kills a player outright.

Format Analysis

Where it lives, where it can’t

FormatVerdict
commander legal
legacy legal
modern legal
pioneer not legal
standard not legal
vintage legal
pauper not legal
oathbreaker legal

Commander is where Skithiryx, the Blight Dragon does its best work — a ten-poison kill requires just two hits on an unmodified player, and haste means opponents have almost no warning. Legacy and Vintage are both legal formats, but competitive lists in those formats don't want a five-mana creature that doesn't win the turn it enters the battlefield without haste mana or pump backup; Skithiryx shows up there only in niche Reanimator shells that can cheat it into play for cheaper. Modern is legal but practically absent for the same reason — five mana is a lot to ask in a format with Fatal Push and Orcish Bowmasters. Oathbreaker is the one other format worth mentioning, where Skithiryx, the Blight Dragon as the Planeswalker signature spell target could set up a fast infect kill in a smaller format.

Key Combos

Combo lines featuring this card

Budget Alternatives

Cheaper options that do most of the same work

No single card fully replicates what Skithiryx, the Blight Dragon does — infect plus haste plus regeneration on a five-power flier is a unique combination — but Phyrexian Crusader covers the infect-with-protection angle at a fraction of the cost, and Blightsteel Colossus is the other direction, delivering a one-hit kill if you can cheat it in. If the goal is specifically a hasted infect threat, Phyrexian Vatmother costs less and threatens poison accumulation faster, but it lacks both flying and the built-in protection that makes Skithiryx a resilient threat rather than a glass cannon.

Price Context

Current price

$11.47 mid tier

At $11.47, Skithiryx, the Blight Dragon sits in the mid tier — expensive enough to feel like a deliberate include but not a budget-breaking slot. Infect commander decks treat it as a near-staple, and that sustained demand keeps the price stable rather than trending down.

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Sources

Mentioned

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Updated . Data from Scryfall, EDHREC, and Commander Spellbook.