Dyadrine, Synthesis Amalgam
Legendary Artifact Creature — Construct
Trample
Dyadrine enters with a number of +1/+1 counters on it equal to the amount of mana spent to cast it.
Whenever you attack, you may remove a +1/+1 counter from each of two creatures you control. If you do, draw a card and create a 2/2 colorless Robot artifact creature token.
- CMC
- 2
- Mana cost
- Color identity
- GW
- Rarity
- rare
- Set
- Edge of Eternities Promos
- Price
- $0.28
- EDHREC rank
- #10131
Dyadrine, Synthesis Amalgam generates mana and counters the moment it enters — the engine starts before you spend another card. The cost is real: it does nothing on its own without creatures already in play, and Crystalline Crawler outclasses it in pure efficiency, so Dyadrine earns its slot specifically in Felothar, Dawn of the Abzan and similar go-wide counter shells where the synergy density justifies the slot.
Best Commanders
Commanders with the highest synergy

Felothar, Dawn of the Abzan
Felothar, Dawn of the Abzan distributes +1/+1 counters aggressively enough that Dyadrine, Synthesis Amalgam enters with a meaningful counter count — turning that board presence directly into mana for the next threat.
Format Analysis
Where it lives, where it can’t
| Format | Verdict |
|---|---|
| commander | legal |
| legacy | legal |
| modern | legal |
| pioneer | legal |
| standard | legal |
| vintage | legal |
| pauper | not legal |
| oathbreaker | legal |
Dyadrine, Synthesis Amalgam is legal in every major constructed format, but it doesn't show up outside Commander — the effect is too conditional and too slow for the tempo demands of Pioneer, Modern, or Legacy. In Commander, it fits narrow but real: +1/+1 counter decks and token-wide strategies can convert a loaded board into a mana spike that accelerates into a game-ending turn. Outside those shells, three mana for a vanilla 2/2 with conditional upside is below the rate the format demands.
Key Combos
Combo lines featuring this card




Dyadrine, Synthesis AmalgamCrystalline CrawlerResourceful DefenseAshnod's Altar
Infinite LTB; Infinite ETB; Infinite sacrifice triggers; Infinite death triggers; Infinite storm count; Infinite commander casts
View on Commander Spellbook ↗



Dyadrine, Synthesis AmalgamCrystalline CrawlerResourceful DefenseKrark-Clan Ironworks
Infinite LTB; Infinite ETB; Infinite sacrifice triggers; Infinite death triggers; Infinite storm count; Infinite commander casts
View on Commander Spellbook ↗




Dyadrine, Synthesis AmalgamCrystalline CrawlerResourceful DefenseMyth UnboundPhyrexian Altar
Infinite LTB; Infinite ETB; Infinite sacrifice triggers; Infinite death triggers; Infinite storm count; Infinite commander casts
View on Commander Spellbook ↗Price Context
Current price
$0.28 bulk tier
At $0.28, Dyadrine, Synthesis Amalgam is bulk — it's cheap enough to throw into any counter-synergy build without a second thought. Bulk rares with narrow but real applications tend to sit in this range indefinitely, so don't expect the price to move unless a future commander pushes the archetype into wider play.
Explore
Sources
Updated . Data from Scryfall, EDHREC, and Commander Spellbook.