Cankerbloom
Creature — Phyrexian Fungus
, Sacrifice this creature: Choose one —
• Destroy target artifact.
• Destroy target enchantment.
• Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
- CMC
- 2
- Mana cost
- Color identity
- G
- Rarity
- uncommon
- Set
- Phyrexia: All Will Be One
- Price
- —
- EDHREC rank
- #707
Cankerbloom enters the battlefield and immediately destroys an artifact or enchantment — or both, if you proliferate the poison counter it arrives with. Ezuri, Stalker of Spheres turns that proliferate into a free draw, making Cankerbloom a two-mana removal spell that replaces itself.
Best Commanders
Commanders with the highest synergy

Ezuri, Stalker of Spheres
Ezuri, Stalker of Spheres draws a card whenever you proliferate, so Cankerbloom's enter-the-battlefield proliferate is effectively stapled to a cantrip — two mana to blow up an artifact or enchantment and replace the card is an easy inclusion.

Ixhel, Scion of Atraxa
Ixhel, Scion of Atraxa cares about stacking poison counters on opponents, and Cankerbloom's proliferate nudges every poisoned player closer to ten while also handling a troublesome enchantment or artifact on the way in.

Vishgraz, the Doomhive
Vishgraz, the Doomhive generates Mite tokens with toxic, so each Cankerbloom proliferate accelerates the poison clock while simultaneously cleaning up a problematic artifact or enchantment the deck can't attack through.

The Mycotyrant
The Mycotyrant rewards proliferate synergies across the board, and Cankerbloom slots in as a flexible piece that handles hate pieces like Rest in Peace or Grafdigger's Cage while also advancing the counter-stacking gameplan.

Fynn, the Fangbearer
Fynn, the Fangbearer kills with deathtouch damage and poison, and Cankerbloom's proliferate can close a game that Fynn's attackers already pushed within reach — doubling as artifact or enchantment removal keeps the slot from feeling like a concession.
Format Analysis
Where it lives, where it can’t
| Format | Verdict |
|---|---|
| commander | legal |
| legacy | legal |
| modern | legal |
| pioneer | legal |
| standard | not legal |
| vintage | legal |
| pauper | not legal |
| oathbreaker | legal |
Cankerbloom is squarely a Commander card — the proliferate payoff only matters when you've built around it, and singleton construction means one well-timed enter-the-battlefield trigger goes a long way. In Modern and Pioneer, Cankerbloom is legal but rarely sees play; Haywire Mite handles artifacts at the same cost without the poison baggage, and most competitive lists want unconditional answers rather than modal creatures. Legacy and Vintage have access to far more efficient artifact and enchantment hate, so Cankerbloom doesn't register there either. Stick to Commander, where proliferate synergies are dense enough to justify the slot.
Key Combos
Combo lines featuring this card
Price Context
Current price
unknown tier
Pricing data for Cankerbloom isn't currently available, so check Scryfall or your preferred retailer for the latest figure. Given its narrow competitive appeal and Commander-specific role, it tends to stay affordable — worth picking up a copy if you're building any poison or proliferate shell.
Explore
Sources
Mentioned
Updated . Data from Scryfall, EDHREC, and Commander Spellbook.