Chaos Mutation

Instant

Exile any number of target creatures controlled by different players. For each creature exiled this way, its controller reveals cards from the top of their library until they reveal a creature card, puts that card onto the battlefield, then puts the rest on the bottom of their library in a random order.

CMC
5
Mana cost
{3}{U}{R}
Color identity
RU
Rarity
rare
Set
Warhammer 40,000 Commander
Price
$0.50
EDHREC rank
#8588
Buy on TCGplayer
Chaos Mutation card art
Chaos Mutation wipes a creature off the board and replaces it with a random one — a removal spell that leaves a body, for four mana. Ian Malcolm, Chaotician makes every chaos trigger matter, so the chaotic replacement isn't a downside; it's the whole point.

Best Commanders

Commanders with the highest synergy

01
Ian Malcolm, Chaotician

Ian Malcolm, Chaotician

34.0% of decks · synergy 0.32

Ian Malcolm, Chaotician is the natural home — his ability generates value off chaotic effects, so Chaos Mutation's randomized replacement feeds the engine directly rather than being a liability you accept.

02
Lilah, Undefeated Slickshot

Lilah, Undefeated Slickshot

27.6% of decks · synergy 0.26

Lilah, Undefeated Slickshot cares about casting instants and sorceries, and Chaos Mutation is an instant that does two things at once — removing a threat and dropping a creature — giving Lilah double the triggers for a single card.

03
Abaddon the Despoiler

Abaddon the Despoiler

26.1% of decks · synergy 0.25

Abaddon the Despoiler rewards casting spells with mana value four or more, and Chaos Mutation hits that threshold exactly while also removing a blocker that would otherwise survive into combat.

04
Magnus the Red

Magnus the Red

16.8% of decks · synergy 0.15

Magnus the Red reduces the cost of instant and sorcery spells, which makes Chaos Mutation cheaper to deploy and easier to slot into a turn where you're also deploying threats.

05
Neera, Wild Mage

Neera, Wild Mage

11.2% of decks · synergy 0.09

Neera, Wild Mage flings spells into random replacements anyway, so Chaos Mutation's chaotic creature swap aligns naturally with a deck that's already embraced variance as a strategy.

Format Analysis

Where it lives, where it can’t

FormatVerdict
commander
legacy
modern
pioneer
standard
vintage
pauper
oathbreaker

Chaos Mutation is a Commander card — the chaotic replacement is too swingy for the deterministic game plans that competitive Constructed demands, and its legality in Legacy and Vintage doesn't translate to real play there. In Commander, four mana for an instant-speed creature removal that leaves a random creature behind is a reasonable rate, especially in chaos-themed or Universes Beyond decks where the random element is a feature. Oathbreaker follows the same logic: playable in the right shell, irrelevant outside it.

Key Combos

Combo lines featuring this card

Price Context

Current price

$0.50 bulk tier

At $0.50, Chaos Mutation sits firmly in bulk territory — easy to pick up without a second thought for any deck that wants it. Bulk rares with narrow homes tend to stay flat, so there's no urgency either way.

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Updated . Data from Scryfall, EDHREC, and Commander Spellbook.